GR78081B - - Google Patents
Info
- Publication number
- GR78081B GR78081B GR66782A GR830166782A GR78081B GR 78081 B GR78081 B GR 78081B GR 66782 A GR66782 A GR 66782A GR 830166782 A GR830166782 A GR 830166782A GR 78081 B GR78081 B GR 78081B
- Authority
- GR
- Greece
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/28—Radicals substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
- C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8027252A FR2496653A1 (fr) | 1980-12-22 | 1980-12-22 | Nouveaux derives aminoalcoyl heterocycliques, leurs procedes de preparation et leur application en therapeutique |
| FR8123304A FR2518087A2 (en) | 1981-12-14 | 1981-12-14 | Aminoalkyl di:hydro-naphthalene, isoquinoline and benzoxazepine cpds. - useful as analgesics and antidepressants |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR78081B true GR78081B (en]) | 1984-09-26 |
Family
ID=26222136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR66782A GR78081B (en]) | 1980-12-22 | 1983-02-03 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US4386090A (en]) |
| AU (1) | AU7875781A (en]) |
| CA (1) | CA1181748A (en]) |
| DE (1) | DE3150876A1 (en]) |
| ES (3) | ES508670A0 (en]) |
| GB (2) | GB2091250B (en]) |
| GR (1) | GR78081B (en]) |
| IT (1) | IT1168074B (en]) |
| LU (1) | LU83850A1 (en]) |
| NL (1) | NL8105791A (en]) |
| SE (1) | SE8107537L (en]) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3244594A1 (de) * | 1982-12-02 | 1984-06-07 | Hoechst Ag, 6230 Frankfurt | 1-phenylisochinolinderivate und verfahren zu ihrer herstellung, diese verbindung enthaltende pharmazeutische praeparate und deren anwendung |
| FR2544718B1 (fr) * | 1983-04-21 | 1985-12-20 | Hexachimie | Diniflumate d'ester morpholinoethylique d'acide niflumique, preparation, utilisation en therapeutique comme analgesique et anti-inflammatoire |
| US4745222A (en) * | 1983-05-25 | 1988-05-17 | Merrell Dow Pharmaceuticals Inc. | Novel aryloxycycloalkanolaminoalkylene aryl ketones |
| DE3413897A1 (de) * | 1984-04-13 | 1985-10-17 | Bayer Ag, 5090 Leverkusen | (beta)-naphthylalkylamine |
| EP0261842B1 (en) * | 1986-09-17 | 1990-11-22 | Dr. Lo. Zambeletti S.p.A. | N1-acylated-(1-(phenyl or benzyl))-1,2-ethylene diamines |
| ZA885824B (en) * | 1987-08-14 | 1989-04-26 | Merrell Dow Pharma | Novel antidepressants |
| US5149714A (en) * | 1987-08-14 | 1992-09-22 | Merrell Dow Pharmaceuticals Inc. | Antidepressants |
| US5561152A (en) * | 1987-08-14 | 1996-10-01 | Merrell Pharmaceuticals Inc. | Antidepressants |
| US5229414A (en) * | 1988-01-21 | 1993-07-20 | Imperial Chemical Industries Plc | Diamine compounds |
| US5071845A (en) * | 1988-12-28 | 1991-12-10 | Suntory Limited | Benzoxazepine derivative |
| US5948820A (en) | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
| IT1303737B1 (it) | 1998-11-11 | 2001-02-23 | Smithkline Beecham Spa | Derivati fenilpiperidinici procedimento per la loro preparazione eloro uso come ligandi del recettore orl-1. |
| US6646012B2 (en) * | 2001-01-16 | 2003-11-11 | Theravance, Inc. | Sodium channel modulators |
| AU2002344820B2 (en) * | 2001-06-20 | 2006-12-14 | Merck & Co., Inc. | Dipeptidyl peptidase inhibitors for the treatment of diabetes |
| WO2003000181A2 (en) * | 2001-06-20 | 2003-01-03 | Merck & Co., Inc. | Dipeptidyl peptidase inhibitors for the treatment of diabetes |
| SI1471054T1 (sl) | 2002-01-11 | 2009-12-31 | Daiichi Sankyo Co Ltd | Amino alkoholni derivati ali derivati fosfoniäśne kisline in medicinski sestavki, ki vsebujejo le-te |
| CA2490818A1 (en) * | 2002-07-15 | 2004-01-22 | Merck & Co., Inc. | Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes |
| ATE370141T1 (de) * | 2002-10-07 | 2007-09-15 | Merck & Co Inc | Antidiabetische heterocyclische beta- aminoverbindungen als inhibitoren von dipeptidylpeptidase |
| AU2003290577B2 (en) * | 2002-11-07 | 2008-12-11 | Merck Sharp & Dohme Corp. | Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| US7309714B2 (en) * | 2002-12-04 | 2007-12-18 | Merck & Co., Inc. | Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| US20060052382A1 (en) * | 2002-12-20 | 2006-03-09 | Duffy Joseph L | 3-Amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| EP1589969A4 (en) * | 2003-01-17 | 2008-08-13 | Merck & Co Inc | 3-AMINO-4-PHENYLBUTANEAN DERIVATEALS DIPEPTIDYLPEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES |
| AU2004210149A1 (en) * | 2003-01-31 | 2004-08-19 | Merck & Co., Inc. | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| CA2524531A1 (en) * | 2003-05-14 | 2004-12-02 | Merck And Co., Inc. | 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| US7332520B2 (en) * | 2003-06-06 | 2008-02-19 | Merck & Co., Inc. | Fused indoles as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes |
| EP1638950A4 (en) * | 2003-06-17 | 2010-06-30 | Merck Sharp & Dohme | CYCLOHEXYLGLYCIN DERIVATIVES AS DIPEPTIDYLPEPTIDASEINHIBITORS FOR THE TREATMENT OF BZW. PREVENTION OF DIABETES |
| DE602004018503D1 (de) * | 2003-07-31 | 2009-01-29 | Merck & Co Inc | Hexahydrodiazepinone als inhibitoren des dipeptidylpeptidase-iv zur behandlung bzw. prävention von diabetes |
| DE602004025132D1 (de) * | 2003-09-18 | 2010-03-04 | Takasago Perfumery Co Ltd | Asymmetrische reduktive aminierung von ketosäurederivaten zur herstellung von aminosäurederivaten |
| CN1870990A (zh) * | 2003-11-04 | 2006-11-29 | 默克公司 | 作为糖尿病治疗或预防用二肽基肽酶iv抑制剂的稠合苯基丙氨酸衍生物 |
| RU2332212C2 (ru) | 2004-02-24 | 2008-08-27 | Санкио Компани, Лимитед | Аминоспирт |
| WO2005108382A1 (en) * | 2004-05-04 | 2005-11-17 | Merck & Co., Inc. | 1,2,4-oxadiazole derivatives as dipeptidyl peptidase-iv inhibitors for the treatment or prevention of diabetes |
| US7618981B2 (en) * | 2004-05-06 | 2009-11-17 | Cytokinetics, Inc. | Imidazopyridinyl-benzamide anti-cancer agents |
| US7504413B2 (en) * | 2004-05-06 | 2009-03-17 | Cytokinetics, Inc. | N-(4-(imidazo[1,2A]pyridin-YL)phenethyl)benzamide inhibitors of the mitotic kinesin CENP-E for treating certain cellular proliferation diseases |
| US7795448B2 (en) * | 2004-05-06 | 2010-09-14 | Cytokinetics, Incorporated | Imidazoyl-benzamide anti-cancer agents |
| EP1604662A1 (en) * | 2004-06-08 | 2005-12-14 | Santhera Pharmaceuticals (Deutschland) Aktiengesellschaft | 1-[(3R)-Amino-4-(2-fluoro-phenyl)-butyl]-pyrrolidine-(2R)-carboxylic acid benzyl amine derivatives and related compounds as dipeptidyl peptidase IV (DPP-IV) inhibitors for the treatment of type 2 diabetes mellitus |
| WO2007056056A2 (en) * | 2005-11-02 | 2007-05-18 | Cytokinetics, Inc. | Mitotic kinesin inhibitors |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2168929A (en) * | 1936-12-12 | 1939-08-08 | Winthrop Chem Co Inc | Isoquinoline compounds and derivatives thereof |
| US3663608A (en) * | 1969-12-10 | 1972-05-16 | Bristol Myers Co | 1-phenyl-3-aminoalkyl-1,2,3,4-tetrahydronaphthalenes and the salts thereof |
| US3704328A (en) * | 1970-01-21 | 1972-11-28 | James S Kaltenbronn | 4- and 5-aryl-1-naphthaleneethanol compounds |
| US3663627A (en) * | 1970-06-01 | 1972-05-16 | Bristol Myers Co | 1-indanmethanols |
| GB1400425A (en) * | 1971-09-22 | 1975-07-16 | Rolland Sa A | Substituted 3-hydroxymethyl-isoquinolines and derivatives |
| US4022791A (en) * | 1975-06-03 | 1977-05-10 | Pfizer Inc. | 2-Aminomethyl-3,4-dihydronaphthalenes |
-
1981
- 1981-12-16 SE SE8107537A patent/SE8107537L/xx not_active Application Discontinuation
- 1981-12-16 US US06/331,484 patent/US4386090A/en not_active Expired - Fee Related
- 1981-12-21 ES ES508670A patent/ES508670A0/es active Granted
- 1981-12-21 IT IT25722/81A patent/IT1168074B/it active
- 1981-12-21 GB GB8138399A patent/GB2091250B/en not_active Expired
- 1981-12-21 CA CA000392859A patent/CA1181748A/en not_active Expired
- 1981-12-22 AU AU78757/81A patent/AU7875781A/en not_active Abandoned
- 1981-12-22 LU LU83850A patent/LU83850A1/fr unknown
- 1981-12-22 NL NL8105791A patent/NL8105791A/xx not_active Application Discontinuation
- 1981-12-22 DE DE19813150876 patent/DE3150876A1/de not_active Withdrawn
-
1982
- 1982-12-16 ES ES518692A patent/ES8400093A1/es not_active Expired
- 1982-12-16 ES ES518693A patent/ES518693A0/es active Granted
-
1983
- 1983-02-03 GR GR66782A patent/GR78081B/el unknown
- 1983-03-08 US US06/473,182 patent/US4431851A/en not_active Expired - Fee Related
- 1983-11-15 US US06/552,181 patent/US4504663A/en not_active Expired - Fee Related
-
1984
- 1984-04-09 GB GB08409163A patent/GB2137992B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| CA1181748A (en) | 1985-01-29 |
| ES8306093A1 (es) | 1983-06-01 |
| NL8105791A (nl) | 1982-07-16 |
| ES508670A0 (es) | 1983-06-01 |
| IT8125722A0 (it) | 1981-12-21 |
| ES8400388A1 (es) | 1983-11-01 |
| AU7875781A (en) | 1982-07-01 |
| US4386090A (en) | 1983-05-31 |
| ES518692A0 (es) | 1983-11-01 |
| ES518693A0 (es) | 1983-11-01 |
| DE3150876A1 (de) | 1982-07-29 |
| GB8409163D0 (en) | 1984-05-16 |
| GB2091250B (en) | 1984-11-14 |
| IT1168074B (it) | 1987-05-20 |
| GB2091250A (en) | 1982-07-28 |
| US4504663A (en) | 1985-03-12 |
| US4431851A (en) | 1984-02-14 |
| ES8400093A1 (es) | 1983-11-01 |
| GB2137992A (en) | 1984-10-17 |
| SE8107537L (sv) | 1982-06-23 |
| LU83850A1 (fr) | 1983-09-02 |
| GB2137992B (en) | 1985-05-09 |